Prevalence of Human Papilloma Virus subtypes 52,56,58,59 and 66 among Yemeni Patients with Cervical Cancer

Saleh Hussein Bensumaidea*, Hussain Gadel karim Ahmed
Department of Pathology, College of Medicine, Hadhramout University of Science and
Technology, Yemen;
Department of Pathology, College of Medicine, Molecular Diagnostics and Personalized Therapeutics Unit, University of Hail, KSA;
Department of Histopathology and Cytology, FMLS, University of Khartoum, Sudan.

Abstract
Background: Knowledge of high risk Human Papilloma Virus (HPV) subtypes might be helpful for development of strategies for decreasing the burden of risk of cervical cancer. Therefore, the aim of this study was to screen for some HR-HPV subtypes that are less common in many regions.
Methodology: A total of 150tissue samples obtained from patients with cervical cancer in addition to 50 tissue
samples obtained from patients with benign cervical lesions, were investigated for the presence of HPV subtypes
52,56,58,59 and 66 by Polymerase Chain Reaction (PCR).
Results: The prevalence of HPV subtypes 52,56,58,59, and 66, among cases was 0.6%, 0%, 4%, 3.3% and 0%
respectively.
Conclusion: HPV subtypes 58 and 59 have a considerable contribution to etiology of cervical cancer in
Yemen that requires further consideration

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